Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50508013![]() (CHEMBL4541479) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Newcastle University Curated by ChEMBL | Assay Description Inhibition of ERK5 in human HeLa cells by KiNativ profiling method | Eur J Med Chem 178: 530-543 (2019) Article DOI: 10.1016/j.ejmech.2019.05.057 BindingDB Entry DOI: 10.7270/Q23F4T0G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50508013![]() (CHEMBL4541479) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01756 BindingDB Entry DOI: 10.7270/Q20R9TH8 | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50508013![]() (CHEMBL4541479) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer AG Curated by ChEMBL | Assay Description Inhibition of His-tagged MAP2K5 activated N-terminal GST-tagged recombinant human ERK5 (1 to 398 residues) expressed in Escherichia coli using biotin... | J Med Chem 62: 928-940 (2019) Article DOI: 10.1021/acs.jmedchem.8b01606 BindingDB Entry DOI: 10.7270/Q2FN19H1 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mitogen-activated protein kinase 7 (Homo sapiens (Human)) | BDBM50508013![]() (CHEMBL4541479) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer AG Curated by ChEMBL | Assay Description Inhibition of ERK5 in human SN12C cells transduced with MEF2-responsive transcription element assessed as reduction in MEF2 transcription by measurin... | J Med Chem 62: 928-940 (2019) Article DOI: 10.1021/acs.jmedchem.8b01606 BindingDB Entry DOI: 10.7270/Q2FN19H1 | |||||||||||
More data for this Ligand-Target Pair |