Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM15952'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM15952 (1-[(4-Amino-5-cyano-6-ethoxypyridin-2-ylcarbamoyl)...) Show SMILES CCCCNC(=O)C1CCN(CC(=O)Nc2cc(N)c(C#N)c(OCC)n2)CC1 Show InChI InChI=1S/C20H30N6O3/c1-3-5-8-23-19(28)14-6-9-26(10-7-14)13-18(27)24-17-11-16(22)15(12-21)20(25-17)29-4-2/h11,14H,3-10,13H2,1-2H3,(H,23,28)(H3,22,24,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...				J Med Chem 49: 3563-80 (2006) Article DOI: 10.1021/jm060199b BindingDB Entry DOI: 10.7270/Q2P26WDX
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