Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50211441'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50211441 (4-(4-(1H-indol-3-yl)pyrimidin-2-ylamino)-N-ethylpi...) Show SMILES CCNC(=O)N1CCC(CC1)Nc1nccc(n1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C20H24N6O/c1-2-21-20(27)26-11-8-14(9-12-26)24-19-22-10-7-18(25-19)16-13-23-17-6-4-3-5-15(16)17/h3-7,10,13-14,23H,2,8-9,11-12H2,1H3,(H,21,27)(H,22,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
UCB Curated by ChEMBL					Assay Description Inhibition of JNK1				Bioorg Med Chem Lett 17: 3463-7 (2007) Article DOI: 10.1016/j.bmcl.2007.03.078 BindingDB Entry DOI: 10.7270/Q2959H7W
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