Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50363463'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50363463 (CHEMBL1946341) Show SMILES COc1ccc(Nc2ncc3nc(Nc4ccccc4F)n(C4CCOCC4)c3n2)cc1 Show InChI InChI=1S/C23H23FN6O2/c1-31-17-8-6-15(7-9-17)26-22-25-14-20-21(29-22)30(16-10-12-32-13-11-16)23(28-20)27-19-5-3-2-4-18(19)24/h2-9,14,16H,10-13H2,1H3,(H,27,28)(H,25,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Celgene Corporation Curated by ChEMBL					Assay Description Inhibition of full length Hexa-His-tagged JNK1 using GST-tagged cJun and [gamma33P]ATP as substrate after 60 mins by scintillation counting				Bioorg Med Chem Lett 22: 1427-32 (2012) Article DOI: 10.1016/j.bmcl.2011.12.028 BindingDB Entry DOI: 10.7270/Q2513ZP6
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