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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase 8' and Ligand = 'BDBM50526695'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 8


(Homo sapiens (Human))		BDBM50526695
PNG
(BI-78D3 | CHEMBL508280)
Show SMILES Oc1nnc(Sc2ncc(s2)[N+]([O-])=O)n1-c1ccc2OCCOc2c1
Show InChI InChI=1S/C13H9N5O5S2/c19-11-15-16-12(25-13-14-6-10(24-13)18(20)21)17(11)7-1-2-8-9(5-7)23-4-3-22-8/h1-2,5-6H,3-4H2,(H,15,19)
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MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 280n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of JNK1 (unknown origin) using ATF2 as substrate after 1 hr by Lanthascreen TR-FRET assay

J Med Chem 62: 6512-6524 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00089
BindingDB Entry DOI: 10.7270/Q25X2DC4
More data for this
Ligand-Target Pair