Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 14' and Ligand = 'BDBM431887'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human))	BDBM431887 (3-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azab...) Show SMILES CN1[C@@H]2C[C@@H]2[C@@](O)(C#Cc2cccc(c2)-c2nc(C(N)=O)n3ccccc23)C1=O |r| Show InChI InChI=1S/C22H18N4O3/c1-25-17-12-15(17)22(29,21(25)28)9-8-13-5-4-6-14(11-13)18-16-7-2-3-10-26(16)20(24-18)19(23)27/h2-7,10-11,15,17,29H,12H2,1H3,(H2,23,27)/t15-,17+,22-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...				US Patent US10550117 (2020) BindingDB Entry DOI: 10.7270/Q2959KZ4
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