Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 14' and Ligand = 'BDBM431888'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 14 (Homo sapiens (Human))	BDBM431888 (1-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azab...) Show SMILES COc1ccn2c(nc(-c3cccc(c3)C#C[C@]3(O)[C@H]4C[C@H]4N(C)C3=O)c2c1)C(N)=O |r| Show InChI InChI=1S/C23H20N4O4/c1-26-17-12-16(17)23(30,22(26)29)8-6-13-4-3-5-14(10-13)19-18-11-15(31-2)7-9-27(18)21(25-19)20(24)28/h3-5,7,9-11,16-17,30H,12H2,1-2H3,(H2,24,28)/t16-,17+,23-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Genentech, Inc. US Patent					Assay Description The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...				US Patent US10550117 (2020) BindingDB Entry DOI: 10.7270/Q2959KZ4
					More data for this Ligand-Target Pair