Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase 7' and Ligand = 'BDBM50514510'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 7 (Homo sapiens (Human))	BDBM50514510 (CHEMBL4442889) Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc(c(Nc3ccccc3NC(=O)C=C)n2)-c2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C36H35N7O2/c1-3-34(44)39-32-11-7-8-12-33(32)40-35-31(26-13-19-30(20-14-26)45-29-9-5-4-6-10-29)25-37-36(41-35)38-27-15-17-28(18-16-27)43-23-21-42(2)22-24-43/h3-20,25H,1,21-24H2,2H3,(H,39,44)(H2,37,38,40,41)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.46E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of tracer 222 binding to recombinant human His-tagged TAK1 (437 to 504 residues) expressed in baculovirus expression system using tyrosine...				J Med Chem 63: 1624-1641 (2020) Article DOI: 10.1021/acs.jmedchem.9b01502 BindingDB Entry DOI: 10.7270/Q2H998J8
					More data for this Ligand-Target Pair