Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mitogen-activated protein kinase kinase kinase kinase 1' and Ligand = 'BDBM587327'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM587327 (US11534441, Compound 35 | US11534441, Compound 36) Show SMILES COc1ncc(c2cc(Nc3ccc4C(=O)OC(C)(C)Cc4n3)ncc12)C(C)(C)N Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	0.170	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...				Citation and Details BindingDB Entry DOI: 10.7270/Q27S7SMZ
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase kinase 1 (Homo sapiens (Human))	BDBM587327 (US11534441, Compound 35 | US11534441, Compound 36) Show SMILES COc1ncc(c2cc(Nc3ccc4C(=O)OC(C)(C)Cc4n3)ncc12)C(C)(C)N Show InChI	PDB NCI pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem	US Patent	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100×, 10-point, 4-fold serial dilution of each inhibitor was created in 1...				Citation and Details BindingDB Entry DOI: 10.7270/Q27S7SMZ
					More data for this Ligand-Target Pair