Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mixed lineage kinase domain-like protein (Homo sapiens) | BDBM5832![]() (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1021/acs.jmedchem.2c01518 BindingDB Entry DOI: 10.7270/Q2QC07MW | ||||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) | ||||||||||||
Mixed lineage kinase domain-like protein (Homo sapiens) | BDBM5832![]() (3-{4-[methyl({2-[(3-sulfamoylphenyl)amino]pyrimidi...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a |
Fudan University Curated by ChEMBL | Assay Description Binding affinity to MLKL (unknown origin) | J Med Chem 63: 1490-1510 (2020) Article DOI: 10.1021/acs.jmedchem.9b01317 BindingDB Entry DOI: 10.7270/Q20K2CZB | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |