Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM280487'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Mus musculus (mouse))	BDBM280487 (US10030020, Example 32 | US10781211, Example 32) Show SMILES CCOc1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)ccc1Cl Show InChI InChI=1S/C21H25ClF6N2O3/c1-2-32-16-12-14(4-5-15(16)22)13-30-9-3-6-19(30)7-10-29(11-8-19)18(31)33-17(20(23,24)25)21(26,27)28/h4-5,12,17H,2-3,6-11,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
					More data for this Ligand-Target Pair
Monoglyceride lipase (Mus musculus (mouse))	BDBM280487 (US10030020, Example 32 | US10781211, Example 32) Show SMILES CCOc1cc(CN2CCCC22CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F)ccc1Cl Show InChI InChI=1S/C21H25ClF6N2O3/c1-2-32-16-12-14(4-5-15(16)22)13-30-9-3-6-19(30)7-10-29(11-8-19)18(31)33-17(20(23,24)25)21(26,27)28/h4-5,12,17H,2-3,6-11,13H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018) BindingDB Entry DOI: 10.7270/Q2FX7CGF
					More data for this Ligand-Target Pair