Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM463778'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Mus musculus (mouse))	BDBM463778 (US10781211, Example 18) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCN(Cc3c(cccc3C(F)(F)F)C3CC4COCC4C3)C2)CC1)C(F)(F)F Show InChI InChI=1S/C27H31F9N2O3/c28-25(29,30)21-3-1-2-19(16-10-17-13-40-14-18(17)11-16)20(21)12-37-7-4-24(15-37)5-8-38(9-6-24)23(39)41-22(26(31,32)33)27(34,35)36/h1-3,16-18,22H,4-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
LUNDBECK LA JOLLA RESEARCH CENTER, INC. US Patent					Assay Description MAGL, ABHD6 and FAAH: Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated...				US Patent US10781211 (2020) BindingDB Entry DOI: 10.7270/Q2RX9G56
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