Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50531974'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531974 (CHEMBL4575018) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1cc(O)ccc1F Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)20-15-19(26)9-10-21(20)24/h5-10,15,18,26H,2-4,11-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-NPA as substrate after 30 mins				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483 BindingDB Entry DOI: 10.7270/Q2GM8BSN
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50531974 (CHEMBL4575018) Show SMILES CCCCc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1cc(O)ccc1F Show InChI InChI=1S/C23H26FNO3/c1-2-3-4-16-5-7-17(8-6-16)22(27)18-11-13-25(14-12-18)23(28)20-15-19(26)9-10-21(20)24/h5-10,15,18,26H,2-4,11-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	431	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of MAGL in human U937 cell homogenates incubated for 5 mins in presence of [1,2,3-3H]2-OG by liquid scintillation spectroscopy				J Med Chem 62: 1932-1958 (2019) Article DOI: 10.1021/acs.jmedchem.8b01483 BindingDB Entry DOI: 10.7270/Q2GM8BSN
					More data for this Ligand-Target Pair