Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50543946'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50543946 (CHEMBL4640364) Show SMILES Fc1ccc(cc1)-n1ncc2cc(ccc12)C(=O)N1CC(C1)N1CCN(CC1)C(=O)c1nccs1 Show InChI InChI=1S/C25H23FN6O2S/c26-19-2-4-20(5-3-19)32-22-6-1-17(13-18(22)14-28-32)24(33)31-15-21(16-31)29-8-10-30(11-9-29)25(34)23-27-7-12-35-23/h1-7,12-14,21H,8-11,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Research & Development, L.L.C. Curated by ChEMBL					Assay Description Reversible inhibition of wild type human MAGL using 4-methylumbelliferyl butyrate as substrate measured after 5 mins by fluorescence assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2020.127243 BindingDB Entry DOI: 10.7270/Q21G0QT6
					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50543946 (CHEMBL4640364) Show SMILES Fc1ccc(cc1)-n1ncc2cc(ccc12)C(=O)N1CC(C1)N1CCN(CC1)C(=O)c1nccs1 Show InChI InChI=1S/C25H23FN6O2S/c26-19-2-4-20(5-3-19)32-22-6-1-17(13-18(22)14-28-32)24(33)31-15-21(16-31)29-8-10-30(11-9-29)25(34)23-27-7-12-35-23/h1-7,12-14,21H,8-11,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of carbonic anhydrase 2 assessed as inhibition of carbon dioxide hydration				Citation and Details
					More data for this Ligand-Target Pair