BindingDB PrimarySearch

Found 3 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase' and Ligand = 'BDBM50562160'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Monoglyceride lipase (Homo sapiens (Human))	BDBM50562160 (CHEMBL4757403) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Competitive inhibition of human recombinant MAGL using varying concentration of 4-nitrophenylacetate as substrate incubated for 30 mins by microplate...				Bioorg Med Chem Lett 13: 1119-23 (2003) Article DOI: 10.1016/j.ejmech.2020.112857 BindingDB Entry DOI: 10.7270/Q2D21X0K
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50562160 (CHEMBL4757403) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Inhibition of human recombinant MAGL using 4-nitrophenylacetate as substrate incubated for 30 mins by microplate reader assay				Bioorg Med Chem Lett 13: 1119-23 (2003) Article DOI: 10.1016/j.ejmech.2020.112857 BindingDB Entry DOI: 10.7270/Q2D21X0K
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair
Monoglyceride lipase (Homo sapiens (Human))	BDBM50562160 (CHEMBL4757403) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	568	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Inhibition of MAGL in human U937 cells assessed as reduction in [3H]glycerol formation using [1,2,3-3H]2-OG as substrate incubated for 15 mins by liq...				Bioorg Med Chem Lett 13: 1119-23 (2003) Article DOI: 10.1016/j.ejmech.2020.112857 BindingDB Entry DOI: 10.7270/Q2D21X0K
Virginia Commonwealth University Curated by ChEMBL					More data for this Ligand-Target Pair