Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM397473'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM397473 (US9988392, Compound 19) Show SMILES COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C1(CC[C@@]35C[C@]1(C)COCc1ccoc1)OC |r,THB:23:22:12.13:19.18,24:22:12.13:19.18| Show InChI InChI=1S/C28H35NO5/c1-25(17-33-15-18-7-12-32-14-18)16-26-8-9-28(25,31-4)24-27(26)10-11-29(2)21(26)13-19-5-6-20(30-3)23(34-24)22(19)27/h5-7,12,14,21,24H,8-11,13,15-17H2,1-4H3/t21-,24-,25-,26-,27+,28?/m1/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	402	n/a	n/a	n/a	n/a
BioCryst Pharmaceuticals					Assay Description μ-Opioid:Radioligand dose-displacement binding assays for μ-opioid receptors used 0.3 nM [3H]-diprenorphine (Perkin Elmer, Shelton, Conn.),...				Bioorg Med Chem 17: 3934-58 (2009) BindingDB Entry DOI: 10.7270/Q28K7CF0
					More data for this Ligand-Target Pair