BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50221416'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£t des Saarlandes Curated by ChEMBL					Assay Description Binding affinity to mu opioid receptor in rat brain membrane				Eur J Med Chem 43: 2307-15 (2008) Article DOI: 10.1016/j.ejmech.2008.02.011 BindingDB Entry DOI: 10.7270/Q2Z60Q02
Universit£t des Saarlandes Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Diabetes and Digestive and Kidney Diseases Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO at mu-opioid receptor				J Med Chem 44: 1471-4 (2001) BindingDB Entry DOI: 10.7270/Q2PK0GVP
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	105	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Maryland Curated by ChEMBL					Assay Description Activity at mu opioid receptor assessed as stimulation of [35S]GTP-gamma-S binding				Bioorg Med Chem Lett 17: 5916-7 (2007) Article DOI: 10.1016/j.bmcl.2007.07.098 BindingDB Entry DOI: 10.7270/Q2RV0NFR
University of Maryland Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description The compound was evaluated for binding affinity against opioid receptor mu in guinea pig brain membranes using [3H]- DAMGO as ligand				J Med Chem 35: 4325-9 (1992) BindingDB Entry DOI: 10.7270/Q2DF6RTZ
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- DAMGO in guinea pig brain membrane of opioid receptor mu				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (GUINEA PIG)	BDBM50221416 (22-methyl-(2S,13R)-14-oxa-11,22-diazaheptacyclo[13...) Show SMILES Show InChI	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	468	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Binding affinity was measured by the displacement of [3H]- DADLE in guinea pig brain membrane of opioid receptor delta				J Med Chem 33: 1714-20 (1990) BindingDB Entry DOI: 10.7270/Q27P9003
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair