Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50521444'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50521444 (CHEMBL4459283) Show SMILES OC(=O)C(F)(F)F.Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCc1cc(Cc2ccccc2)ccc1OCc1ccccc1 |r| Show InChI InChI=1S/C32H34N2O3.C2HF3O2/c1-22-15-28(35)16-23(2)29(22)19-30(33)32(36)34-20-27-18-26(17-24-9-5-3-6-10-24)13-14-31(27)37-21-25-11-7-4-8-12-25;3-2(4,5)1(6)7/h3-16,18,30,35H,17,19-21,33H2,1-2H3,(H,34,36);(H,6,7)/t30-;/m0./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Displacement of [3H]-diprenorphine from rat mu-type opioid receptor expressed in rat C6 cell membranes incubated for 1 hr in shaker by liquid scintil...				J Med Chem 62: 4142-4157 (2019) Article DOI: 10.1021/acs.jmedchem.9b00219 BindingDB Entry DOI: 10.7270/Q23R0X7F
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Rattus norvegicus (rat))	BDBM50521444 (CHEMBL4459283) Show SMILES OC(=O)C(F)(F)F.Cc1cc(O)cc(C)c1C[C@H](N)C(=O)NCc1cc(Cc2ccccc2)ccc1OCc1ccccc1 |r| Show InChI InChI=1S/C32H34N2O3.C2HF3O2/c1-22-15-28(35)16-23(2)29(22)19-30(33)32(36)34-20-27-18-26(17-24-9-5-3-6-10-24)13-14-31(27)37-21-25-11-7-4-8-12-25;3-2(4,5)1(6)7/h3-16,18,30,35H,17,19-21,33H2,1-2H3,(H,34,36);(H,6,7)/t30-;/m0./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	107	n/a	n/a	n/a	n/a
University of Michigan Curated by ChEMBL					Assay Description Agonist activity at rat Mu-type opioid receptor expressed in rat C6 cell membranes assessed as stimulation of [35S]GTPgammaS binding incubated for 1 ...				J Med Chem 62: 4142-4157 (2019) Article DOI: 10.1021/acs.jmedchem.9b00219 BindingDB Entry DOI: 10.7270/Q23R0X7F
					More data for this Ligand-Target Pair