Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 3.83E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.2nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20mg membrane protein/w... | US Patent US8846929 (2014) BindingDB Entry DOI: 10.7270/Q2G44P04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.45E+3 | -30.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purdue Pharma, L.P.; Shionogi & Co., Ltd. US Patent | Assay Description In vitro binding assay using ORL-1m Mu-opioid, kappa-opioid, and delta-opioid receptor. | US Patent US8476271 (2013) BindingDB Entry DOI: 10.7270/Q2416VNB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.45E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.4 | n/a |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description Radioligand dose-displacement binding assays for u-opioid receptors used 0.2nM[3H]-diprenorphine (NEN, Boston, Mass.), with 5-20mg membrane protein/w... | US Patent US8846929 (2014) BindingDB Entry DOI: 10.7270/Q2G44P04 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4.45E+3 | -30.5 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description mu-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for mu-opioid receptors used 0.2 nM[3H]-diprenorphine (NEN,... | US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM97711 (US8476271, 17 | US8846929, 360 | US8846929, 361 | ...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | 7.4 | 25 |
Purdue Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description Mu-Opioid Receptor Functional Assay Procedures: [35S]GTP gamma S functional assays were conducted using freshly thawed mu-receptor membranes. Assay r... | US Patent US9145408 (2015) BindingDB Entry DOI: 10.7270/Q2DJ5DD3 | |||||||||||
More data for this Ligand-Target Pair |