Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1' and Ligand = 'BDBM487587'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487587 (N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...) Show SMILES FC(F)(F)c1c(cnn1-c1cccc2ncccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1 Show InChI InChI=1S/C21H12ClF3N8O/c22-15-9-12(10-27-19(15)33-28-7-8-29-33)31-20(34)14-11-30-32(18(14)21(23,24)25)17-5-1-4-16-13(17)3-2-6-26-16/h1-11H,(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487587 (N-(5-chloro-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl...) Show SMILES FC(F)(F)c1c(cnn1-c1cccc2ncccc12)C(=O)Nc1cnc(c(Cl)c1)-n1nccn1 Show InChI InChI=1S/C21H12ClF3N8O/c22-15-9-12(10-27-19(15)33-28-7-8-29-33)31-20(34)14-11-30-32(18(14)21(23,24)25)17-5-1-4-16-13(17)3-2-6-26-16/h1-11H,(H,31,34)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair