Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1' and Ligand = 'BDBM487661'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487661 (N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...) Show SMILES FC(F)(F)c1c(cnn1-c1cccc2ncccc12)C(=O)Nc1cnc(c(c1)C#N)-n1nccn1 Show InChI InChI=1S/C22H12F3N9O/c23-22(24,25)19-16(12-31-33(19)18-5-1-4-17-15(18)3-2-6-27-17)21(35)32-14-9-13(10-26)20(28-11-14)34-29-7-8-30-34/h1-9,11-12H,(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487661 (N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...) Show SMILES FC(F)(F)c1c(cnn1-c1cccc2ncccc12)C(=O)Nc1cnc(c(c1)C#N)-n1nccn1 Show InChI InChI=1S/C22H12F3N9O/c23-22(24,25)19-16(12-31-33(19)18-5-1-4-17-15(18)3-2-6-27-17)21(35)32-14-9-13(10-26)20(28-11-14)34-29-7-8-30-34/h1-9,11-12H,(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
					More data for this Ligand-Target Pair