Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1' and Ligand = 'BDBM487730'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (Homo sapiens (Human))	BDBM487730 (N-(5-cyano-6-(2H-1,2,3-triazol- 2-yl)pyridin-3-yl)...) Show SMILES FC(F)(F)c1c(cnn1-c1ccnc2ccccc12)C(=O)Nc1ccc(c(c1)C#N)-n1nccn1 Show InChI InChI=1S/C23H13F3N8O/c24-23(25,26)21-17(13-31-33(21)20-7-8-28-18-4-2-1-3-16(18)20)22(35)32-15-5-6-19(14(11-15)12-27)34-29-9-10-30-34/h1-11,13H,(H,32,35)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description MALT1 protease activity was assessed in an in vitro assay using a tetrapeptide as substrate and full-length MALT1 protein (Strep-MALT1(1-824)-His) pu...				US Patent US10954214 (2021) BindingDB Entry DOI: 10.7270/Q2SX6HB1
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