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Found 1 hit Enz. Inhib. hit(s) with Target = 'Mucosa-associated lymphoid tissue lymphoma translocation protein 1' and Ligand = 'BDBM50516127'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Mucosa-associated lymphoid tissue lymphoma translocation protein 1


(Homo sapiens (Human))
BDBM50516127
PNG
(CHEMBL4559304)
Show SMILES Clc1cccnc1N1CCC(CC1)C(=O)Nc1cc(Cl)c2OCC(=O)Nc2c1
Show InChI InChI=1S/C19H18Cl2N4O3/c20-13-2-1-5-22-18(13)25-6-3-11(4-7-25)19(27)23-12-8-14(21)17-15(9-12)24-16(26)10-28-17/h1-2,5,8-9,11H,3-4,6-7,10H2,(H,23,27)(H,24,26)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 20n/an/an/an/an/an/a



Janssen Research & Development, LLC

Curated by ChEMBL


Assay Description
Inhibition of strep-tagged and His-tagged full length MALT1 protease (1 to 824 residues) (unknown origin) expressed in baculovirus infected insect ce...


Bioorg Med Chem Lett 29: (2019)


Article DOI: 10.1016/j.bmcl.2019.126743
BindingDB Entry DOI: 10.7270/Q2DV1P7R
More data for this
Ligand-Target Pair