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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50424116'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(RAT)		BDBM50424116
PNG
(CHEMBL2315681)
Show SMILES Clc1ccccc1CN1C2CCC1CC(C2)N1CCC(CC1)n1c2ccccc2[nH]c1=O |THB:16:14:8:10.11|
Show InChI InChI=1S/C26H31ClN4O/c27-23-6-2-1-5-18(23)17-30-20-9-10-21(30)16-22(15-20)29-13-11-19(12-14-29)31-25-8-4-3-7-24(25)28-26(31)32/h1-8,19-22H,9-17H2,(H,28,32)
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Article
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n/an/a 950n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at rat muscarinic M1 receptor expressed in CHO cells assessed as inhibition of Ach-induced calcium response

Bioorg Med Chem Lett 23: 223-7 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.132
BindingDB Entry DOI: 10.7270/Q2TM7CF9
More data for this
Ligand-Target Pair