Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M1' and Ligand = 'BDBM50464184'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50464184 (CHEMBL4237601) Show SMILES Cn1ccc2c(Cc3ccc(cc3)-c3nccs3)cc(nc12)C(=O)N[C@@H]1CCOC[C@H]1O |r| Show InChI InChI=1S/C24H24N4O3S/c1-28-9-6-18-17(12-15-2-4-16(5-3-15)24-25-8-11-32-24)13-20(26-22(18)28)23(30)27-19-7-10-31-14-21(19)29/h2-6,8-9,11,13,19,21,29H,7,10,12,14H2,1H3,(H,27,30)/t19-,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.62E+3	n/a	n/a	n/a	n/a
Vanderbilt Univercity Curated by ChEMBL					Assay Description Agonist activity at rat M1 receptor expressed in CHO cells assessed as increase in calcium mobilization measured after 2.5 mins by Fluo-4-AM dye base...				ACS Med Chem Lett 9: 917-922 (2018) Article DOI: 10.1021/acsmedchemlett.8b00261 BindingDB Entry DOI: 10.7270/Q2RJ4N44
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50464184 (CHEMBL4237601) Show SMILES Cn1ccc2c(Cc3ccc(cc3)-c3nccs3)cc(nc12)C(=O)N[C@@H]1CCOC[C@H]1O |r| Show InChI InChI=1S/C24H24N4O3S/c1-28-9-6-18-17(12-15-2-4-16(5-3-15)24-25-8-11-32-24)13-20(26-22(18)28)23(30)27-19-7-10-31-14-21(19)29/h2-6,8-9,11,13,19,21,29H,7,10,12,14H2,1H3,(H,27,30)/t19-,21-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	89	n/a	n/a	n/a	n/a
Vanderbilt Univercity Curated by ChEMBL					Assay Description Agonist activity at human M1 receptor expressed in CHO cells assessed as increase in calcium mobilization measured after 2.5 mins by Fluo-4-AM dye ba...				ACS Med Chem Lett 9: 917-922 (2018) Article DOI: 10.1021/acsmedchemlett.8b00261 BindingDB Entry DOI: 10.7270/Q2RJ4N44
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50464184 (CHEMBL4237601) Show SMILES Cn1ccc2c(Cc3ccc(cc3)-c3nccs3)cc(nc12)C(=O)N[C@@H]1CCOC[C@H]1O |r| Show InChI InChI=1S/C24H24N4O3S/c1-28-9-6-18-17(12-15-2-4-16(5-3-15)24-25-8-11-32-24)13-20(26-22(18)28)23(30)27-19-7-10-31-14-21(19)29/h2-6,8-9,11,13,19,21,29H,7,10,12,14H2,1H3,(H,27,30)/t19-,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Vanderbilt Univercity Curated by ChEMBL					Assay Description Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...				ACS Med Chem Lett 9: 917-922 (2018) Article DOI: 10.1021/acsmedchemlett.8b00261 BindingDB Entry DOI: 10.7270/Q2RJ4N44
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50464184 (CHEMBL4237601) Show SMILES Cn1ccc2c(Cc3ccc(cc3)-c3nccs3)cc(nc12)C(=O)N[C@@H]1CCOC[C@H]1O |r| Show InChI InChI=1S/C24H24N4O3S/c1-28-9-6-18-17(12-15-2-4-16(5-3-15)24-25-8-11-32-24)13-20(26-22(18)28)23(30)27-19-7-10-31-14-21(19)29/h2-6,8-9,11,13,19,21,29H,7,10,12,14H2,1H3,(H,27,30)/t19-,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	5.62E+3	n/a	n/a	n/a	n/a
Vanderbilt Univercity Curated by ChEMBL					Assay Description Agonist activity at rat M1 receptor expressed in CHO cells assessed as increase in calcium mobilization measured after 2.5 mins by Fluo-4-AM dye base...				ACS Med Chem Lett 9: 917-922 (2018) Article DOI: 10.1021/acsmedchemlett.8b00261 BindingDB Entry DOI: 10.7270/Q2RJ4N44
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (RAT)	BDBM50464184 (CHEMBL4237601) Show SMILES Cn1ccc2c(Cc3ccc(cc3)-c3nccs3)cc(nc12)C(=O)N[C@@H]1CCOC[C@H]1O |r| Show InChI InChI=1S/C24H24N4O3S/c1-28-9-6-18-17(12-15-2-4-16(5-3-15)24-25-8-11-32-24)13-20(26-22(18)28)23(30)27-19-7-10-31-14-21(19)29/h2-6,8-9,11,13,19,21,29H,7,10,12,14H2,1H3,(H,27,30)/t19-,21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	100	n/a	n/a	n/a	n/a
Vanderbilt Univercity Curated by ChEMBL					Assay Description Positive allosteric modulation of rat M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretreate...				ACS Med Chem Lett 9: 917-922 (2018) Article DOI: 10.1021/acsmedchemlett.8b00261 BindingDB Entry DOI: 10.7270/Q2RJ4N44
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50464184 (CHEMBL4237601) Show SMILES Cn1ccc2c(Cc3ccc(cc3)-c3nccs3)cc(nc12)C(=O)N[C@@H]1CCOC[C@H]1O |r| Show InChI InChI=1S/C24H24N4O3S/c1-28-9-6-18-17(12-15-2-4-16(5-3-15)24-25-8-11-32-24)13-20(26-22(18)28)23(30)27-19-7-10-31-14-21(19)29/h2-6,8-9,11,13,19,21,29H,7,10,12,14H2,1H3,(H,27,30)/t19-,21-/m1/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
Vanderbilt Univercity Curated by ChEMBL					Assay Description Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as increase in acetylcholine-induced calcium mobilization pretrea...				ACS Med Chem Lett 9: 917-922 (2018) Article DOI: 10.1021/acsmedchemlett.8b00261 BindingDB Entry DOI: 10.7270/Q2RJ4N44
					More data for this Ligand-Target Pair