Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M3' and Ligand = 'BDBM50208046'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M3 (Homo sapiens (Human))	BDBM50208046 (1-methyl-3-(R)-3-[4,4-bis-(4-fluoro-phenyl)-2-oxo-...) Show SMILES C[N+]1(CC(=O)c2cccnc2)CC[C@H](C1)N1CC(NC1=O)(c1ccc(F)cc1)c1ccc(F)cc1 Show InChI InChI=1S/C27H26F2N4O2/c1-33(17-25(34)19-3-2-13-30-15-19)14-12-24(16-33)32-18-27(31-26(32)35,20-4-8-22(28)9-5-20)21-6-10-23(29)11-7-21/h2-11,13,15,24H,12,14,16-18H2,1H3/p+1/t24-,33?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Via Zambeletti 25 Curated by ChEMBL					Assay Description Displacement of [3H]N-methyl-scopalamine from human muscarinic M3 receptor expressed in CHOK1 cells				J Med Chem 50: 1693-7 (2007) Article DOI: 10.1021/jm061160+ BindingDB Entry DOI: 10.7270/Q2M32VF5
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