Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM372260'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (RAT)	BDBM372260 (2-[4-[[(3,4-Dimethylpyrimido[4',5':4,5]thieno[2,3-...) Show SMILES Cc1nnc2sc3c(NCc4ccc(cc4)C(C)(C)O)ncnc3c2c1C Show InChI InChI=1S/C20H21N5OS/c1-11-12(2)24-25-19-15(11)16-17(27-19)18(23-10-22-16)21-9-13-5-7-14(8-6-13)20(3,4)26/h5-8,10,26H,9H2,1-4H3,(H,21,22,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	23	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...				J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q2W09880
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM372260 (2-[4-[[(3,4-Dimethylpyrimido[4',5':4,5]thieno[2,3-...) Show SMILES Cc1nnc2sc3c(NCc4ccc(cc4)C(C)(C)O)ncnc3c2c1C Show InChI InChI=1S/C20H21N5OS/c1-11-12(2)24-25-19-15(11)16-17(27-19)18(23-10-22-16)21-9-13-5-7-14(8-6-13)20(3,4)26/h5-8,10,26H,9H2,1-4H3,(H,21,22,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	52	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...				J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q2W09880
					More data for this Ligand-Target Pair