Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM372270'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (RAT)	BDBM372270 (8-(3-azabicyclo[3.1.0] hexan-3-yl)-3,4- dimethylpy...) Show SMILES Cc1nnc2sc3c(ncnc3c2c1C)N1CC2CC2C1 Show InChI InChI=1S/C15H15N5S/c1-7-8(2)18-19-15-11(7)12-13(21-15)14(17-6-16-12)20-4-9-3-10(9)5-20/h6,9-10H,3-5H2,1-2H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	36	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...				J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q2W09880
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM372270 (8-(3-azabicyclo[3.1.0] hexan-3-yl)-3,4- dimethylpy...) Show SMILES Cc1nnc2sc3c(ncnc3c2c1C)N1CC2CC2C1 Show InChI InChI=1S/C15H15N5S/c1-7-8(2)18-19-15-11(7)12-13(21-15)14(17-6-16-12)20-4-9-3-10(9)5-20/h6,9-10H,3-5H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Merck Research Laboratories					Assay Description For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...				J Med Chem 48: 6169-73 (2005) BindingDB Entry DOI: 10.7270/Q2W09880
					More data for this Ligand-Target Pair