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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50423944'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M4


(Homo sapiens (Human))		BDBM50423944
PNG
(CHEMBL2313400)
Show SMILES COc1ccc(NC(=O)c2sc3nc(C)c(Cl)c(C)c3c2N)cc1
Show InChI InChI=1S/C17H16ClN3O2S/c1-8-12-14(19)15(24-17(12)20-9(2)13(8)18)16(22)21-10-4-6-11(23-3)7-5-10/h4-7H,19H2,1-3H3,(H,21,22)
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Article
PubMed
n/an/an/an/a>1.00E+4n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...

Bioorg Med Chem Lett 23: 346-50 (2012)


Article DOI: 10.1016/j.bmcl.2012.10.073
BindingDB Entry DOI: 10.7270/Q2N29Z8S
More data for this
Ligand-Target Pair