Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M4' and Ligand = 'BDBM50502351'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M4 (Homo sapiens (Human))	BDBM50502351 (CHEMBL4474926) Show SMILES CCNC(=O)N1CCCC(CC1)N1CCC(CC1)c1ncccc1OC Show InChI InChI=1S/C20H32N4O2/c1-3-21-20(25)24-12-5-6-17(10-15-24)23-13-8-16(9-14-23)19-18(26-2)7-4-11-22-19/h4,7,11,16-17H,3,5-6,8-10,12-15H2,1-2H3,(H,21,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	>5.99E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human Muscarinic acetylcholine receptor M4 expressed in HEK cells co-expressing Glosensor construct assessed as decrease in isopr...				ACS Med Chem Lett 10: 941-948 (2019) Article DOI: 10.1021/acsmedchemlett.9b00106 BindingDB Entry DOI: 10.7270/Q2GM8BJH
					More data for this Ligand-Target Pair