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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M5' and Ligand = 'BDBM50497834'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M5


(Homo sapiens (Human))		BDBM50497834
PNG
(CHEMBL3323284)
Show SMILES [Br-].[Br-].[H][C@]12O[C@@]1([H])[C@]1([H])C[C@H](C[C@@]2([H])[N+]1(C)CCCCCC[N+](C)(C)CC(C)(C)CN1C(=O)c2cccc3cccc(C1=O)c23)OC(=O)[C@H](CO)c1ccccc1 |r,THB:15:14:5.3:11.10.9,16:14:5.3:11.10.9|
Show InChI InChI=1S/C42H55N3O6.2BrH/c1-42(2,26-43-39(47)31-19-13-17-29-18-14-20-32(36(29)31)40(43)48)27-44(3,4)21-11-6-7-12-22-45(5)34-23-30(24-35(45)38-37(34)51-38)50-41(49)33(25-46)28-15-9-8-10-16-28;;/h8-10,13-20,30,33-35,37-38,46H,6-7,11-12,21-27H2,1-5H3;2*1H/q+2;;/p-2/t30-,33-,34+,35-,37+,38-,45?;;/m1../s1
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PC cid
PC sid
UniChem
Article
PubMed
 5.5n/an/an/an/an/an/an/an/a



University of W£rzburg

Curated by ChEMBL


Assay Description
Displacement of [3H]-NMS from wild-type human muscarinic M5 receptor expressed in CHO-K1 cells by liquid scintillation counting

J Med Chem 57: 6739-50 (2014)


Article DOI: 10.1021/jm500790x
BindingDB Entry DOI: 10.7270/Q2RJ4NGM
More data for this
Ligand-Target Pair