Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Muscarinic acetylcholine receptor M5' and Ligand = 'BDBM50518556'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscarinic acetylcholine receptor M5 (Homo sapiens (Human))	BDBM50518556 (CHEMBL4577453) Show SMILES Fc1ccc(CCCOC(=O)N(C2CN3CCC2CC3)c2ccccc2)cc1F |TLB:11:12:15.16:18.19,(80.95,-52.51,;79.59,-53.23,;79.54,-54.77,;78.18,-55.49,;76.88,-54.66,;75.51,-55.39,;74.21,-54.57,;72.85,-55.29,;71.54,-54.47,;70.18,-55.19,;70.13,-56.73,;68.88,-54.38,;67.52,-55.1,;67.17,-56.53,;65.68,-56.02,;65.67,-53.99,;66.27,-52.73,;66.3,-54.65,;64.6,-55.1,;64.2,-56.54,;68.93,-52.84,;70.3,-52.12,;70.35,-50.58,;69.05,-49.76,;67.68,-50.49,;67.63,-52.03,;76.92,-53.14,;78.28,-52.41,;78.33,-50.87,)| Show InChI InChI=1S/C23H26F2N2O2/c24-20-9-8-17(15-21(20)25)5-4-14-29-23(28)27(19-6-2-1-3-7-19)22-16-26-12-10-18(22)11-13-26/h1-3,6-9,15,18,22H,4-5,10-14,16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Kentucky Curated by ChEMBL					Assay Description Displacement of [3H]NMS from human M5 AChR expressed in CHO cell membranes after 1 to 2 hrs by liquid scintillation spectrometry method				Bioorg Med Chem Lett 29: 471-476 (2019) Article DOI: 10.1016/j.bmcl.2018.12.022 BindingDB Entry DOI: 10.7270/Q2NP27SC
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