Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'N-acylethanolamine-hydrolyzing acid amidase' and Ligand = 'BDBM50439657'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439657 (CHEMBL2419826 | US9353075, 40) Show SMILES CCCCCCCOC(=O)N[C@@H]1[C@H](C)OC1=O |r| Show InChI InChI=1S/C12H21NO4/c1-3-4-5-6-7-8-16-12(15)13-10-9(2)17-11(10)14/h9-10H,3-8H2,1-2H3,(H,13,15)/t9-,10+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	7.4	n/a
The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” US Patent					Assay Description Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...				US Patent US9353075 (2016) BindingDB Entry DOI: 10.7270/Q23N229Q
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439657 (CHEMBL2419826 | US9353075, 40) Show SMILES CCCCCCCOC(=O)N[C@@H]1[C@H](C)OC1=O |r| Show InChI InChI=1S/C12H21NO4/c1-3-4-5-6-7-8-16-12(15)13-10-9(2)17-11(10)14/h9-10H,3-8H2,1-2H3,(H,13,15)/t9-,10+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...				J Med Chem 56: 6917-34 (2013) Article DOI: 10.1021/jm400739u BindingDB Entry DOI: 10.7270/Q2F47QK0
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439657 (CHEMBL2419826 | US9353075, 40) Show SMILES CCCCCCCOC(=O)N[C@@H]1[C@H](C)OC1=O |r| Show InChI InChI=1S/C12H21NO4/c1-3-4-5-6-7-8-16-12(15)13-10-9(2)17-11(10)14/h9-10H,3-8H2,1-2H3,(H,13,15)/t9-,10+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method				J Med Chem 57: 10101-11 (2014) Article DOI: 10.1021/jm501455s BindingDB Entry DOI: 10.7270/Q26111W8
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439657 (CHEMBL2419826 | US9353075, 40) Show SMILES CCCCCCCOC(=O)N[C@@H]1[C@H](C)OC1=O |r| Show InChI InChI=1S/C12H21NO4/c1-3-4-5-6-7-8-16-12(15)13-10-9(2)17-11(10)14/h9-10H,3-8H2,1-2H3,(H,13,15)/t9-,10+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method				J Med Chem 57: 10101-11 (2014) Article DOI: 10.1021/jm501455s BindingDB Entry DOI: 10.7270/Q26111W8
					More data for this Ligand-Target Pair