Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'N-acylethanolamine-hydrolyzing acid amidase' and Ligand = 'BDBM50439661'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439661 (CHEMBL2419822 | US9353075, 5) Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCc1ccccc1 |r| Show InChI InChI=1S/C15H19NO4/c1-11-13(14(17)20-11)16-15(18)19-10-6-5-9-12-7-3-2-4-8-12/h2-4,7-8,11,13H,5-6,9-10H2,1H3,(H,16,18)/t11-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	389	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method				J Med Chem 57: 10101-11 (2014) Article DOI: 10.1021/jm501455s BindingDB Entry DOI: 10.7270/Q26111W8
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439661 (CHEMBL2419822 | US9353075, 5) Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCc1ccccc1 |r| Show InChI InChI=1S/C15H19NO4/c1-11-13(14(17)20-11)16-15(18)19-10-6-5-9-12-7-3-2-4-8-12/h2-4,7-8,11,13H,5-6,9-10H2,1H3,(H,16,18)/t11-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...				J Med Chem 56: 6917-34 (2013) Article DOI: 10.1021/jm400739u BindingDB Entry DOI: 10.7270/Q2F47QK0
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439661 (CHEMBL2419822 | US9353075, 5) Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCc1ccccc1 |r| Show InChI InChI=1S/C15H19NO4/c1-11-13(14(17)20-11)16-15(18)19-10-6-5-9-12-7-3-2-4-8-12/h2-4,7-8,11,13H,5-6,9-10H2,1H3,(H,16,18)/t11-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	390	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Italiano di Tecnologia Curated by ChEMBL					Assay Description Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS method				J Med Chem 57: 10101-11 (2014) Article DOI: 10.1021/jm501455s BindingDB Entry DOI: 10.7270/Q26111W8
					More data for this Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (Rattus norvegicus (Rat))	BDBM50439661 (CHEMBL2419822 | US9353075, 5) Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCc1ccccc1 |r| Show InChI InChI=1S/C15H19NO4/c1-11-13(14(17)20-11)16-15(18)19-10-6-5-9-12-7-3-2-4-8-12/h2-4,7-8,11,13H,5-6,9-10H2,1H3,(H,16,18)/t11-,13+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	390	n/a	n/a	n/a	n/a	7.4	n/a
The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo” US Patent					Assay Description Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...				US Patent US9353075 (2016) BindingDB Entry DOI: 10.7270/Q23N229Q
					More data for this Ligand-Target Pair