Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with Target = 'N-formyl peptide receptor 2' and Ligand = 'BDBM50520823'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50520823 (CHEMBL4434857) Show SMILES CCCCC[C@H](O)c1nc(oc1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C)-c1ccccc1 |r| Show InChI InChI=1S/C26H37NO6/c1-4-5-7-13-22(30)25-23(33-26(27-25)19-11-8-6-9-12-19)17-16-21(29)20(28)14-10-15-24(31)32-18(2)3/h6,8-9,11-12,16-18,20-22,28-30H,4-5,7,10,13-15H2,1-3H3/b17-16+/t20-,21+,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
University College Dublin Curated by ChEMBL					Assay Description Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring re...				Eur J Med Chem 162: 80-108 (2019) Article DOI: 10.1016/j.ejmech.2018.10.049 BindingDB Entry DOI: 10.7270/Q2PV6PS9
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50520823 (CHEMBL4434857) Show SMILES CCCCC[C@H](O)c1nc(oc1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C)-c1ccccc1 |r| Show InChI InChI=1S/C26H37NO6/c1-4-5-7-13-22(30)25-23(33-26(27-25)19-11-8-6-9-12-19)17-16-21(29)20(28)14-10-15-24(31)32-18(2)3/h6,8-9,11-12,16-18,20-22,28-30H,4-5,7,10,13-15H2,1-3H3/b17-16+/t20-,21+,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
University College Dublin Curated by ChEMBL					Assay Description Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring re...				Eur J Med Chem 162: 80-108 (2019) Article DOI: 10.1016/j.ejmech.2018.10.049 BindingDB Entry DOI: 10.7270/Q2PV6PS9
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50520823 (CHEMBL4434857) Show SMILES CCCCC[C@H](O)c1nc(oc1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C)-c1ccccc1 |r| Show InChI InChI=1S/C26H37NO6/c1-4-5-7-13-22(30)25-23(33-26(27-25)19-11-8-6-9-12-19)17-16-21(29)20(28)14-10-15-24(31)32-18(2)3/h6,8-9,11-12,16-18,20-22,28-30H,4-5,7,10,13-15H2,1-3H3/b17-16+/t20-,21+,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
University College Dublin Curated by ChEMBL					Assay Description Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring re...				Eur J Med Chem 162: 80-108 (2019) Article DOI: 10.1016/j.ejmech.2018.10.049 BindingDB Entry DOI: 10.7270/Q2PV6PS9
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50520823 (CHEMBL4434857) Show SMILES CCCCC[C@H](O)c1nc(oc1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C)-c1ccccc1 |r| Show InChI InChI=1S/C26H37NO6/c1-4-5-7-13-22(30)25-23(33-26(27-25)19-11-8-6-9-12-19)17-16-21(29)20(28)14-10-15-24(31)32-18(2)3/h6,8-9,11-12,16-18,20-22,28-30H,4-5,7,10,13-15H2,1-3H3/b17-16+/t20-,21+,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
University College Dublin Curated by ChEMBL					Assay Description Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring re...				Eur J Med Chem 162: 80-108 (2019) Article DOI: 10.1016/j.ejmech.2018.10.049 BindingDB Entry DOI: 10.7270/Q2PV6PS9
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50520823 (CHEMBL4434857) Show SMILES CCCCC[C@H](O)c1nc(oc1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C)-c1ccccc1 |r| Show InChI InChI=1S/C26H37NO6/c1-4-5-7-13-22(30)25-23(33-26(27-25)19-11-8-6-9-12-19)17-16-21(29)20(28)14-10-15-24(31)32-18(2)3/h6,8-9,11-12,16-18,20-22,28-30H,4-5,7,10,13-15H2,1-3H3/b17-16+/t20-,21+,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
University College Dublin Curated by ChEMBL					Assay Description Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation by measuring re...				Eur J Med Chem 162: 80-108 (2019) Article DOI: 10.1016/j.ejmech.2018.10.049 BindingDB Entry DOI: 10.7270/Q2PV6PS9
					More data for this Ligand-Target Pair
N-formyl peptide receptor 2 (Homo sapiens (Human))	BDBM50520823 (CHEMBL4434857) Show SMILES CCCCC[C@H](O)c1nc(oc1\C=C\[C@@H](O)[C@@H](O)CCCC(=O)OC(C)C)-c1ccccc1 |r| Show InChI InChI=1S/C26H37NO6/c1-4-5-7-13-22(30)25-23(33-26(27-25)19-11-8-6-9-12-19)17-16-21(29)20(28)14-10-15-24(31)32-18(2)3/h6,8-9,11-12,16-18,20-22,28-30H,4-5,7,10,13-15H2,1-3H3/b17-16+/t20-,21+,22-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University College Dublin Curated by ChEMBL					Assay Description Agonist activity at ALX/FPR2 in human THP1 cells harboring NF-kB-Luc assessed as inhibition of LPS-induced NFkB signalling activation pretreated for ...				Eur J Med Chem 162: 80-108 (2019) Article DOI: 10.1016/j.ejmech.2018.10.049 BindingDB Entry DOI: 10.7270/Q2PV6PS9
					More data for this Ligand-Target Pair