Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase HST2' and Ligand = 'BDBM50304354'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase HST2 (Saccharomyces cerevisiae)	BDBM50304354 (3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...) Show SMILES OC(=O)CCN1Cc2ccccc2C1=O Show InChI InChI=1S/C11H11NO3/c13-10(14)5-6-12-7-8-3-1-2-4-9(8)11(12)15/h1-4H,5-7H2,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Noncompetitive inhibition of yeast Hst2 using NAD+ substrate				Bioorg Med Chem 17: 7031-41 (2009) Article DOI: 10.1016/j.bmc.2009.07.073 BindingDB Entry DOI: 10.7270/Q21V5FWG
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase HST2 (Saccharomyces cerevisiae)	BDBM50304354 (3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...) Show SMILES OC(=O)CCN1Cc2ccccc2C1=O Show InChI InChI=1S/C11H11NO3/c13-10(14)5-6-12-7-8-3-1-2-4-9(8)11(12)15/h1-4H,5-7H2,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Noncompetitive inhibition of yeast Hst2 using Acetyl-lysine substrate				Bioorg Med Chem 17: 7031-41 (2009) Article DOI: 10.1016/j.bmc.2009.07.073 BindingDB Entry DOI: 10.7270/Q21V5FWG
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase HST2 (Saccharomyces cerevisiae)	BDBM50304354 (3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...) Show SMILES OC(=O)CCN1Cc2ccccc2C1=O Show InChI InChI=1S/C11H11NO3/c13-10(14)5-6-12-7-8-3-1-2-4-9(8)11(12)15/h1-4H,5-7H2,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of yeast Hst2 by fluorimetric assay				Bioorg Med Chem 17: 7031-41 (2009) Article DOI: 10.1016/j.bmc.2009.07.073 BindingDB Entry DOI: 10.7270/Q21V5FWG
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase HST2 (Saccharomyces cerevisiae)	BDBM50304354 (3-(1-Oxo-1,3-dihydro-isoindol-2-yl)-propionic acid...) Show SMILES OC(=O)CCN1Cc2ccccc2C1=O Show InChI InChI=1S/C11H11NO3/c13-10(14)5-6-12-7-8-3-1-2-4-9(8)11(12)15/h1-4H,5-7H2,(H,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	1.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute Curated by ChEMBL					Assay Description Inhibition of yeast Hst2 by fluorimetric assay				Bioorg Med Chem 17: 7031-41 (2009) Article DOI: 10.1016/j.bmc.2009.07.073 BindingDB Entry DOI: 10.7270/Q21V5FWG
					More data for this Ligand-Target Pair