Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-1' and Ligand = 'BDBM50070581'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50070581 (CHEMBL3408830) Show SMILES CCCCCCCCn1c2CCN(Cc3ccccc3)Cc2c2cc(ccc12)-c1cccc(C)c1 Show InChI InChI=1S/C33H40N2/c1-3-4-5-6-7-11-20-35-32-18-17-29(28-16-12-13-26(2)22-28)23-30(32)31-25-34(21-19-33(31)35)24-27-14-9-8-10-15-27/h8-10,12-18,22-23H,3-7,11,19-21,24-25H2,1-2H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
National University of Singapore Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 assessed as deacetylation of N-acetyl lysine residue in p53 (317 to 320) after 30 mins by luciferase-mediated l...				Eur J Med Chem 92: 145-55 (2015) Article DOI: 10.1016/j.ejmech.2014.12.027 BindingDB Entry DOI: 10.7270/Q270834V
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