Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM50156759'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50156759 (5-((2-(3,5-dichloro-2-hydroxybenzylideneamino)phen...) Show SMILES Cc1ncc(CSc2ccccc2\N=C\c2cc(Cl)cc(Cl)c2O)c(CO)c1O Show InChI InChI=1S/C21H18Cl2N2O3S/c1-12-20(27)16(10-26)14(9-24-12)11-29-19-5-3-2-4-18(19)25-8-13-6-15(22)7-17(23)21(13)28/h2-9,26-28H,10-11H2,1H3/b25-8+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of Sirt2				Bioorg Med Chem 19: 3605-15 (2011) Article DOI: 10.1016/j.bmc.2011.01.029 BindingDB Entry DOI: 10.7270/Q2SN0992
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50156759 (5-((2-(3,5-dichloro-2-hydroxybenzylideneamino)phen...) Show SMILES Cc1ncc(CSc2ccccc2\N=C\c2cc(Cl)cc(Cl)c2O)c(CO)c1O Show InChI InChI=1S/C21H18Cl2N2O3S/c1-12-20(27)16(10-26)14(9-24-12)11-29-19-5-3-2-4-18(19)25-8-13-6-15(22)7-17(23)21(13)28/h2-9,26-28H,10-11H2,1H3/b25-8+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of SIRT2				J Med Chem 49: 7907-11 (2006) Article DOI: 10.1021/jm060566j BindingDB Entry DOI: 10.7270/Q2G73FHM
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50156759 (5-((2-(3,5-dichloro-2-hydroxybenzylideneamino)phen...) Show SMILES Cc1ncc(CSc2ccccc2\N=C\c2cc(Cl)cc(Cl)c2O)c(CO)c1O Show InChI InChI=1S/C21H18Cl2N2O3S/c1-12-20(27)16(10-26)14(9-24-12)11-29-19-5-3-2-4-18(19)25-8-13-6-15(22)7-17(23)21(13)28/h2-9,26-28H,10-11H2,1H3/b25-8+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of human recombinant GST-tagged SIRT2 by histone deacetylase assay				J Med Chem 47: 6292-8 (2004) Article DOI: 10.1021/jm049933m BindingDB Entry DOI: 10.7270/Q2S1820Z
					More data for this Ligand-Target Pair