BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM50241183'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50241183 ((E)-N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of SIRT2				Bioorg Med Chem Lett 17: 2448-51 (2007) Article DOI: 10.1016/j.bmcl.2007.02.023 BindingDB Entry DOI: 10.7270/Q2CR5V53
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50241183 ((E)-N-(2-(1H-indol-3-yl)ethyl)-4-(3-(4-(benzyloxy)...) Show SMILES Show InChI	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Kuopio Curated by ChEMBL					Assay Description Inhibition of recombinant GST-tagged SIRT2 (unknown origin) by Fluor de Lys fluorescence assay				Bioorg Med Chem 16: 8054-62 (2008) Article DOI: 10.1016/j.bmc.2008.07.059 BindingDB Entry DOI: 10.7270/Q2TB16QS
University of Kuopio Curated by ChEMBL					More data for this Ligand-Target Pair