Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human)) | BDBM50267654![]() (CHEMBL4104634) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.94E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Laboratoire de Biologie Moléculaire et Cellulaire du Cancer, Hôpital Kirchberg , 9, Rue Edward Steichen, L-2540 Luxembourg, Luxembourg. Curated by ChEMBL | Assay Description Inhibition of N-terminal His-tagged recombinant human SIRT-2 expressed in Escherichia coli using Fluor-de-Lys-SIRT1 as substrate after 15 mins by flu... | J Med Chem 60: 4714-4733 (2017) Article DOI: 10.1021/acs.jmedchem.7b00533 BindingDB Entry DOI: 10.7270/Q23X894D | |||||||||||
More data for this Ligand-Target Pair |