Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-2' and Ligand = 'BDBM50350510'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50350510 (CHEMBL1814815) Show SMILES CC(=O)NCCC[C@H](NC(=O)[C@H](CCCCNC(C)=S)NC(=O)[C@H](CCCNC(C)=O)NC(C)=O)C(N)=O |r| Show InChI InChI=1S/C24H43N7O6S/c1-15(32)26-13-7-10-19(22(25)35)30-24(37)21(9-5-6-12-28-18(4)38)31-23(36)20(29-17(3)34)11-8-14-27-16(2)33/h19-21H,5-14H2,1-4H3,(H2,25,35)(H,26,32)(H,27,33)(H,28,38)(H,29,34)(H,30,37)(H,31,36)/t19-,20-,21-/m0/s1	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Akron Curated by ChEMBL					Assay Description Inhibition of human full length SIRT2 using H2N-MPSD-AcK-TIGG-COOH as substrate assessed as enzymatic deacetylation product formation after 60 mins b...				Bioorg Med Chem Lett 21: 4753-7 (2011) Article DOI: 10.1016/j.bmcl.2011.06.069 BindingDB Entry DOI: 10.7270/Q2DB827S
					More data for this Ligand-Target Pair