Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Homo sapiens (Human)) | BDBM3175![]() (3-[1-[3-(Amidinothio)propyl]-3-indolyl]-4-(1-methy...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet ![]() | Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Ernst-Moritz-Arndt-University Greifswald Curated by ChEMBL | Assay Description Inhibition of human C-terminally His6-tagged Sirt3 using ZMAL as substrate after 4 hrs by homogeneous fluorescent deacetylase assay | Bioorg Med Chem 19: 3669-77 (2011) Article DOI: 10.1016/j.bmc.2011.01.026 BindingDB Entry DOI: 10.7270/Q2XD121S | |||||||||||
More data for this Ligand-Target Pair |