Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacylase sirtuin-6' and Ligand = 'BDBM50528214'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacylase sirtuin-6 (Homo sapiens (Human))	BDBM50528214 (CHEMBL4592529) Show SMILES COc1ccc(c(Cl)c1Cl)S(=O)(=O)Nc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C20H15Cl2F3N2O5S2/c1-32-16-9-10-17(19(22)18(16)21)34(30,31)26-13-5-7-15(8-6-13)33(28,29)27-14-4-2-3-12(11-14)20(23,24)25/h2-11,26-27H,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	2.18E+5	n/a	n/a	n/a	n/a
Shanghai Jiao-Tong University School of Medicine Curated by ChEMBL					Assay Description Inhibition of SIRT6 (unknown origin)				J Med Chem 62: 6405-6421 (2019) Article DOI: 10.1021/acs.jmedchem.8b01749 BindingDB Entry DOI: 10.7270/Q2C53Q9M
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