Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Neprilysin/Angiotensin-converting enzyme' and Ligand = 'BDBM458423'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin/Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM458423 (US10744104, Example 14F | US11547687, Example 14F ...) Show SMILES CCOC(=O)C(=O)NN(C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C20H20ClFN2O6/c1-2-30-20(29)18(26)23-24(11-17(25)19(27)28)10-12-3-5-13(6-4-12)15-9-14(21)7-8-16(15)22/h3-9,17,25H,2,10-11H2,1H3,(H,23,26)(H,27,28)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	US Patent	3.55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assays were performed in 384-well white opaque plates at 37° C. using the fluorogenic peptide substrates at a concentration of 10 μM in Assa...				Citation and Details BindingDB Entry DOI: 10.7270/Q2BG2STK
					More data for this Ligand-Target Pair
Neprilysin/Angiotensin-converting enzyme (Homo sapiens (Human))	BDBM458423 (US10744104, Example 14F | US11547687, Example 14F ...) Show SMILES CCOC(=O)C(=O)NN(C[C@@H](O)C(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C20H20ClFN2O6/c1-2-30-20(29)18(26)23-24(11-17(25)19(27)28)10-12-3-5-13(6-4-12)15-9-14(21)7-8-16(15)22/h3-9,17,25H,2,10-11H2,1H3,(H,23,26)(H,27,28)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem		5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2PR8136
					More data for this Ligand-Target Pair