Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM299647'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM299647 ((2R,4R)-2-Amino-5-(5′-chloro-2′-fluoro...) Show SMILES CC(C)c1coc(n1)C(=O)N[C@@H](C[C@@H](N=[N+]=[N-])C(O)=O)Cc1ccc(cc1)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C24H23ClFN5O4/c1-13(2)21-12-35-23(29-21)22(32)28-17(11-20(24(33)34)30-31-27)9-14-3-5-15(6-4-14)18-10-16(25)7-8-19(18)26/h3-8,10,12-13,17,20H,9,11H2,1-2H3,(H,28,32)(H,33,34)/t17-,20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Theravence Biopharma R&D IP, LLC US Patent					Assay Description Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...				US Patent US9593110 (2017) BindingDB Entry DOI: 10.7270/Q2MC9224
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