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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50038625'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Neprilysin


(Oryctolagus cuniculus (rabbit))		BDBM50038625
PNG
(1-(2-sec-Butyl-4-mercapto-5-phenyl-pentanoyl)-pyrr...)
Show SMILES CCC(C)C(CC(S)Cc1ccccc1)C(=O)N1CCCC1C(O)=O
Show InChI InChI=1S/C20H29NO3S/c1-3-14(2)17(13-16(25)12-15-8-5-4-6-9-15)19(22)21-11-7-10-18(21)20(23)24/h4-6,8-9,14,16-18,25H,3,7,10-13H2,1-2H3,(H,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 350n/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Tested for inhibitory potency against neutral endopeptidase (NEP)

J Med Chem 37: 1865-73 (1994)


BindingDB Entry DOI: 10.7270/Q2474BG6
More data for this
Ligand-Target Pair