Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50064114'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50064114 ((S)-3-Biphenyl-4-yl-2-[(S)-5-(2-fluoro-phenyl)-2-(...) Show SMILES OC(=O)[C@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)[C@H](CC#Cc1ccccc1F)NCP(O)(O)=O Show InChI InChI=1S/C27H26FN2O6P/c28-23-11-5-4-9-22(23)10-6-12-24(29-18-37(34,35)36)26(31)30-25(27(32)33)17-19-13-15-21(16-14-19)20-7-2-1-3-8-20/h1-5,7-9,11,13-16,24-25,29H,12,17-18H2,(H,30,31)(H,32,33)(H2,34,35,36)/t24-,25-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharmaceuticals Corporation Curated by ChEMBL					Assay Description Inhibitory activity against neutral endopeptidase (NEP).				J Med Chem 41: 1513-23 (1998) Article DOI: 10.1021/jm970787c BindingDB Entry DOI: 10.7270/Q2PV6M1M
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