Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neprilysin' and Ligand = 'BDBM50287145'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neprilysin (Homo sapiens (Human))	BDBM50287145 ((R)-2-{2-Benzyl-3-[((R)-1-benzyloxycarbonylamino-2...) Show SMILES OC(=O)[C@@H](Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(=O)[C@H](Cc1ccccc1)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C35H37N2O7P/c38-33(36-31(34(39)40)22-27-15-7-2-8-16-27)30(21-26-13-5-1-6-14-26)25-45(42,43)32(23-28-17-9-3-10-18-28)37-35(41)44-24-29-19-11-4-12-20-29/h1-20,30-32H,21-25H2,(H,36,38)(H,37,41)(H,39,40)(H,42,43)/t30?,31-,32-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	>6.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of neutral endopeptidase in human umbilical vein endothelial cells				Bioorg Med Chem Lett 6: 1323-1326 (1996) Article DOI: 10.1016/0960-894X(96)00227-2 BindingDB Entry DOI: 10.7270/Q2Q81DKV
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