Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neurogenic locus notch homolog protein 3' and Ligand = 'BDBM50074699'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurogenic locus notch homolog protein 3 (Homo sapiens (Human))	BDBM50074699 (CHEMBL3410156) Show SMILES NC(=O)[C@H]([C@@H](CCC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2NC1=O)c1cocn1 |r,t:15| Show InChI InChI=1S/C25H22F3N5O4/c26-25(27,28)11-10-16(19(21(29)34)18-12-37-13-30-18)23(35)33-22-24(36)31-17-9-5-4-8-15(17)20(32-22)14-6-2-1-3-7-14/h1-9,12-13,16,19,22H,10-11H2,(H2,29,34)(H,31,36)(H,33,35)/t16-,19-,22-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
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