Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Neurogenic locus notch homolog protein 3' and Ligand = 'BDBM50074702'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurogenic locus notch homolog protein 3 (Homo sapiens (Human))	BDBM50074702 (CHEMBL3410154) Show SMILES CCC[C@@H]([C@@H](CC(F)(F)F)C(=O)N[C@H]1N=C(c2ccccc2)c2ccccc2N(C)C1=O)C(N)=O |r,t:14| Show InChI InChI=1S/C25H27F3N4O3/c1-3-9-16(21(29)33)18(14-25(26,27)28)23(34)31-22-24(35)32(2)19-13-8-7-12-17(19)20(30-22)15-10-5-4-6-11-15/h4-8,10-13,16,18,22H,3,9,14H2,1-2H3,(H2,29,33)(H,31,34)/t16-,18+,22+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Research and Development Curated by ChEMBL					Assay Description Inhibition of Notch3 intracellular domain fragment transfected in human HeLa cells co-transfected with CBF1-PGL3 luciferase reporter vector by transa...				Bioorg Med Chem Lett 25: 1905-9 (2015) Article DOI: 10.1016/j.bmcl.2015.03.038 BindingDB Entry DOI: 10.7270/Q2X92D18
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